4.0
ISS Score
D — Higher caution — limited safety data
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · odorant · masking agent
Cyclamen Aldehyde
Molecular Formula
C13H18O
Molecular Weight
190.28 g/mol
Category
fragrance
Bottom Line: Cyclamen Aldehyde is generally considered safe in cosmetics and household products, though some individuals may experience sensitivity.
Quick Answer
✔ Generally Safe If:
- used in low concentrations
- properly diluted in formulations
- not used on broken skin
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you have a history of allergies
✕ Avoid If:
- you experience irritation or allergic reactions
- you are using it in high concentrations
- you have respiratory issues
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C13H18O |
| Molecular Weight | 190.28 g/mol |
| Solubility | Soluble (in ethanol) |
| Log P | 3.3 |
Common Use Cases
3 Categories
Cosmetic
Perfumes, body lotions, shampoos. Use in low concentrations to minimize irritation risk.
Household
Air fresheners, cleaning products. Ensure proper ventilation when using products containing this ingredient.
Pharmaceutical
Topical ointments, medicated creams. Consult a healthcare provider if unsure about use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Cyclamen Aldehyde may cause mild irritation upon skin contact in some individuals.
oral
oral
Risk Level: Moderate
Ingestion of Cyclamen Aldehyde can lead to gastrointestinal irritation and toxicity.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation may cause respiratory irritation; effects vary by exposure level.
ocular
ocular
Risk Level: High
Eye contact with Cyclamen Aldehyde can cause significant irritation and damage.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of adverse reactions due to developing systems.
- pregnant — Potential risks to fetal development; caution advised.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with proper use.
- sensitive_skin — May tolerate with precautions like patch testing.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated, but individual sensitivities may vary. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | Very High | Higher sensitivity to chemicals; potential for severe reactions. |
| breastfeeding | Moderate | Limited data on excretion in breast milk; caution is warranted. |
| sensitive_skin | High | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Cyclamen Aldehyde is a fragrance ingredient with moderate safety assessments supporting its use in cosmetics and household products.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2012) |
| Skin Irritation | non-irritating | Human patch test | Not a skin irritant | SCCS Opinion (2015) |
| Sensitization | no sensitization observed | Human clinical study | Low sensitization potential | FDA Regulatory Review (2020) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Cyclamen Aldehyde is a fragrance ingredient with moderate safety assessments supporting its use in cosmetics and household products.
- Generally recognized as safe in low concentrations.
- May cause irritation in sensitive individuals.
- Regulatory bodies have assessed its safety.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Cyclamen Aldehyde
Year: 2012
Conclusion: Safe for use in cosmetics at concentrations up to 0.5%.
View Full Report →
SCCS
Report: Opinion on Cyclamen Aldehyde
Year: 2015
Conclusion: Considered safe for use in cosmetic products with appropriate restrictions.
View Full Report →
FDA
Report: Regulatory Status of Cyclamen Aldehyde
Year: 2020
Conclusion: No restrictions on use in cosmetics; generally recognized as safe.
View Full Report →
Regulatory Status
Global
Cyclamen Aldehyde is permitted in the US and UK, with restrictions in the EU. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionRESTRICTED
Use limited to cosmetic products at concentrations up to 0.5%.
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaNO_DATA
No specific regulations found.
Frequently Asked Questions
Cyclamen Aldehyde may cause irritation in sensitive individuals; patch testing is recommended.
Consult a healthcare provider before using products containing Cyclamen Aldehyde if pregnant.
Potential side effects include skin irritation and allergic reactions in sensitive individuals.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T04:56:43.755405Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.