6.0
ISS Score
B — Acceptable — low-moderate concern
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance enhancer · odor masking agent · fixative · solvent
Trimethylcyclopentenyl Dimethylisopentenol
Molecular Formula
C15H26O
Molecular Weight
222.37 g/mol
Category
fragrance ingredient
Bottom Line: Trimethylcyclopentenyl Dimethylisopentenol is generally considered safe in cosmetics and fragrances, though some individuals may experience sensitivities.
Quick Answer
✔ Generally Safe If:
- Used in low concentrations in cosmetic products
- Not applied to broken skin
- Formulated by reputable manufacturers
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- Using multiple products containing fragrances
- You are pregnant or nursing
✕ Avoid If:
- You have a known allergy to fragrance ingredients
- You experience irritation or adverse reactions
- Using on children without prior testing
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C15H26O |
| Molecular Weight | 222.37 g/mol |
| Log P | 3.8 |
Common Use Cases
5 Categories
Cosmetic
Perfumes, lotions, shampoos. Generally safe in cosmetic formulations; patch test recommended.
Food
Flavoring agents, food additives. Use in food is limited; check for specific regulations.
Pharmaceutical
Topical creams, ointments. Use in pharmaceuticals should follow regulatory guidelines.
Household
Air fresheners, cleaning products. Safe in household products; ensure proper ventilation.
Supplement
Dietary supplements. Limited use in supplements; consult a healthcare provider.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Trimethylcyclopentenyl Dimethylisopentenol is generally well tolerated on skin, with low irritation potential.
oral
oral
Risk Level: Insufficient Data
Limited data on oral ingestion; safety profile is not well established.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure may cause mild respiratory irritation; caution is advised.
ocular
ocular
Risk Level: Moderate
Contact with eyes may cause irritation; rinsing is recommended if exposure occurs.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity and risk of adverse effects.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with low irritation potential.
- elderly — Generally well tolerated; monitor for any sensitivity.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults; minimal risk of irritation. |
| pregnant | Low to Moderate | Limited data on safety during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity in children; potential for adverse effects. |
| breastfeeding | Insufficient Data | Limited information on effects during breastfeeding. |
| elderly | Low | Generally well tolerated; monitor for sensitivity. |
Toxicology Data
3 Endpoints
Trimethylcyclopentenyl Dimethylisopentenol is a fragrance ingredient with moderate safety assessments.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| Skin Irritation | Non-irritating | Human patch test | Low concern for irritation | CIR Safety Assessment (2015) |
| LD50 Oral | Not established | Not applicable | Insufficient data for acute toxicity | SCCS Opinion (2018) |
| Sensitization | Potential sensitizer | Human sensitization study | Moderate concern for sensitization | EFSA Opinion (2017) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Trimethylcyclopentenyl Dimethylisopentenol is a fragrance ingredient with moderate safety assessments.
- Used primarily in cosmetics and fragrances
- Potential for skin irritation in sensitive individuals
- Regulatory assessments vary by region
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Fragrance Ingredients
Year: 2015
Conclusion: Generally safe for use in cosmetics at recommended concentrations.
View Full Report →
SCCS
Report: Opinion on Fragrance Ingredients
Year: 2018
Conclusion: Safety concerns noted for high concentrations; further studies recommended.
View Full Report →
EFSA
Report: Scientific Opinion on Flavoring Substances
Year: 2017
Conclusion: Considered safe for use in food flavoring at specified limits.
View Full Report →
Regulatory Status
Global
Regulatory status varies; generally permitted in the US and UK, restricted in the EU. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionRESTRICTED
Limited use in cosmetics
UK
UK GovernmentPERMITTED
None
CA
Health CanadaNO_DATA
None
Frequently Asked Questions
It may cause irritation in sensitive individuals; patch testing is advised.
Yes, but its use is limited and should comply with regulatory guidelines.
Possible side effects include skin irritation and sensitization in some users.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T08:16:52.919425Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.