7.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · flavoring agent
Allylanisole
Molecular Formula
C10H12O
Molecular Weight
148.20 g/mol
Category
fragrance
Bottom Line: Generally regarded as safe for use in cosmetics and food, though individual sensitivities may occur.
Quick Answer
✔ Generally Safe If:
- used in low concentrations
- applied to intact skin
- not combined with known irritants
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you are using other fragrances
✕ Avoid If:
- you have a known allergy to similar compounds
- you experience irritation or allergic reactions
- you are using on broken skin
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C10H12O |
| Molecular Weight | 148.20 g/mol |
| Boiling Point | 215.0°C |
| Solubility | Soluble (in ethanol) |
| Density | 0.965 g/cm³ |
| Log P | 3.4 |
Common Use Cases
4 Categories
Cosmetic
Fragrances, lotions, shampoos. Use in moderation to avoid potential skin irritation.
Food
Flavoring agents, beverages. Generally safe when used within recommended limits.
Pharmaceutical
Topical creams, medicated ointments. Consult a healthcare provider for use in medications.
Supplement
Dietary supplements. Safety in supplements is less established; use cautiously.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Allylanisole is generally well tolerated on the skin with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion of allylanisole may cause gastrointestinal discomfort in some individuals.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk but may cause irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation and discomfort.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk due to developing systems and potential for adverse reactions.
- pregnant — Caution advised due to limited safety data during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with low risk of adverse effects.
- elderly — Generally well tolerated, but individual responses may vary.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated; however, individual sensitivities may vary. |
| pregnant | Moderate | Limited data on safety during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity to chemicals; potential for adverse effects. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| elderly | Low | Generally well tolerated, but monitor for any unusual reactions. |
Toxicology Data
3 Endpoints
Allylanisole is a fragrance ingredient with a favorable safety profile in cosmetics and food applications.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | — | Insufficient data for acute toxicity | — |
| Skin Irritation | Non-irritating | Human patch test | Low irritation potential | CIR Safety Assessment (2015) |
| Sensitization | Not sensitizing | Human patch test | Low sensitization potential | CIR Safety Assessment (2015) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Allylanisole is a fragrance ingredient with a favorable safety profile in cosmetics and food applications.
- Widely used in cosmetic and food products.
- Generally recognized as safe by regulatory bodies.
- Potential for skin irritation in sensitive individuals.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Allylanisole
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 1%.
View Full Report →
EFSA
Report: Scientific Opinion on Allylanisole
Year: 2018
Conclusion: Considered safe for use as a food flavoring agent.
View Full Report →
FDA
Report: Food Additive Status
Year: 2020
Conclusion: Generally recognized as safe when used appropriately.
View Full Report →
Regulatory Status
Global
Allylanisole is generally permitted across major jurisdictions with no significant restrictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
Generally, yes, but individuals with sensitive skin should proceed with caution.
Yes, it is recognized as safe for use as a flavoring agent in food.
Discontinue use immediately and consult a healthcare professional if irritation persists.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T04:01:06.023472Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.