4.0
ISS Score
D — Higher caution — limited safety data
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · flavoring agent · solvent · emollient
Allyl Heptanoate
Molecular Formula
C10H18O2
Molecular Weight
170.25 g/mol
Category
ester
Bottom Line: Allyl Heptanoate is generally considered safe for use in cosmetics and food, though individual sensitivities may occur.
Quick Answer
✔ Generally Safe If:
- Used in concentrations below 1% in cosmetics
- Ingested as part of food flavoring within regulatory limits
- No known allergies to similar esters
- Used in well-formulated products
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- Using multiple products containing esters
- Pregnant or breastfeeding
- You are using it for the first time
✕ Avoid If:
- You have a known allergy to Allyl Heptanoate
- Using on broken or irritated skin
- Ingesting in large quantities outside food use
- Using in products for children without guidance
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C10H18O2 |
| Molecular Weight | 170.25 g/mol |
| Boiling Point | 210.0°C |
| Solubility | 1ml in 1ml 95% ethanol (in ethanol) |
| Log P | 3.2 |
Common Use Cases
3 Categories
Cosmetic
Fragrance oils, lotions, shampoos. Generally safe in cosmetic formulations under 1%.
Food
Flavoring agents, beverages, confectionery. Used as a flavoring agent within regulatory limits.
Supplement
Dietary supplements, nutraceuticals. Consult a healthcare provider before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Allyl Heptanoate is generally well tolerated on skin, but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of Allyl Heptanoate may lead to gastrointestinal discomfort in some individuals.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but may cause respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation and should be avoided.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of adverse reactions due to developing systems.
- pregnant — Limited safety data; potential risks to fetal development.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal adverse effects.
- breastfeeding — Generally low risk, but caution is advised.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated, but individual sensitivities may vary. |
| pregnant | Moderate | Limited data on safety during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity to chemicals; potential for adverse effects. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; caution is recommended. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Allyl Heptanoate is assessed for safety in cosmetics and food, showing low toxicity and good safety profiles.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Human patch test | No irritation observed | SCCS Opinion (2017) |
| Sensitization | not sensitizing | Human sensitization study | No sensitization reactions | EFSA Opinion (2018) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Allyl Heptanoate is assessed for safety in cosmetics and food, showing low toxicity and good safety profiles.
- Low acute toxicity in animal studies.
- Generally recognized as safe in food applications.
- No significant adverse effects reported in cosmetic use.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Allyl Heptanoate
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 1%.
View Full Report →
EFSA
Report: Scientific Opinion on Allyl Heptanoate
Year: 2018
Conclusion: Considered safe for use as a food flavoring agent.
View Full Report →
SCCS
Report: Opinion on Allyl Heptanoate
Year: 2017
Conclusion: No safety concerns at recommended concentrations.
View Full Report →
Regulatory Status
Global
Regulatory restrictions apply in some jurisdictions. Annex III entry 139; no maximum concentration is recorded in CosIng for this entry; check the entry's conditions of use Switch to Detailed mode for full regulatory breakdown.
European Union
European CommissionRESTRICTED IN COSMETICS (ANNEX III, ENTRY 139)
Annex III entry 139; no maximum concentration is recorded in CosIng for this entry; check the entry's conditions of use
US
FDAPERMITTED
None
UK
UK GovernmentPERMITTED
None
CA
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform a patch test first.
Yes, it is used as a flavoring agent in food, but always within recommended limits.
Discontinue use immediately and consult a healthcare professional if irritation persists.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T04:05:49.536241Z | — | Initial data enrichment via 3-phase structured outputs |
| Regulatory status correction | 2026-10-29T21:31:21.036632+00:00 | 4.0 | EU regulatory status replaced with the CosIng Annex entry; the safety score was not re-evaluated. |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.