7.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · flavoring agent · solvent · stabilizer
2-Benzylideneoctanal
Molecular Formula
C15H20O
Molecular Weight
216.32 g/mol
Category
fragrance
Bottom Line: 2-Benzylideneoctanal is generally considered safe for use in cosmetics and food, though some individuals may experience sensitivities.
Quick Answer
✔ Generally Safe If:
- Used in low concentrations in cosmetic formulations
- Not applied to broken skin
- Used in well-ventilated areas
- Not combined with known allergens
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- You are pregnant or nursing
- You are using multiple fragrance products
- You have a history of respiratory issues
✕ Avoid If:
- You are allergic to fragrance ingredients
- You have eczema or dermatitis
- You are using on children without testing
- You experience irritation upon application
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C15H20O |
| Molecular Weight | 216.32 g/mol |
| Melting Point | 4.0°C |
| Solubility | miscible (in ethanol) |
| Log P | 4.8 |
Common Use Cases
4 Categories
Cosmetic
Fragrances, lotions, shampoos. Use in moderation to avoid skin irritation.
Food
Flavoring agents, beverages. Generally recognized as safe when used appropriately.
Pharmaceutical
Topical creams, ointments. Consult a healthcare provider for use in medications.
Supplement
Dietary supplements. Use under guidance of a healthcare professional.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to 2-Benzylideneoctanal is generally low risk for skin contact.
oral
oral
Risk Level: Moderate
Ingestion of 2-Benzylideneoctanal may pose moderate risks, particularly in high doses.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low to moderate risk, depending on concentration.
ocular
ocular
Risk Level: High
Eye contact with 2-Benzylideneoctanal can cause irritation and is considered high risk.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures.
- pregnant — Limited data on safety during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated in healthy adults.
- elderly — Generally well tolerated, but health factors vary.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no significant health issues. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposures. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; caution is advised. |
| elderly | Low | Generally well tolerated, but individual health factors should be considered. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
2-Benzylideneoctanal has been assessed for safety in cosmetics and food applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Human patch test | No significant irritation observed | SCCS Opinion (2018) |
| Sensitization | positive in some individuals | Human sensitization study | Potential sensitizer | EFSA Opinion (2017) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
2-Benzylideneoctanal has been assessed for safety in cosmetics and food applications, showing low toxicity.
- Low acute toxicity in animal studies
- Potential skin sensitizer in some individuals
- Regulatory reviews support safe use in specified concentrations
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of 2-Benzylideneoctanal
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 0.5%.
View Full Report →
SCCS
Report: Opinion on 2-Benzylideneoctanal
Year: 2018
Conclusion: Considered safe for use in cosmetics with restrictions.
View Full Report →
EFSA
Report: Scientific Opinion on 2-Benzylideneoctanal
Year: 2017
Conclusion: Acceptable daily intake established for food use.
View Full Report →
Regulatory Status
Global
2-Benzylideneoctanal is permitted in cosmetics and food, with some restrictions in the EU. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionRESTRICTED
Limited to cosmetic use at specified concentrations
UK
UK GovernmentPERMITTED
None
CA
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, it may cause irritation in sensitive individuals.
Consult a healthcare provider before using products containing this ingredient during pregnancy.
Discontinue use immediately and consult a healthcare professional if irritation persists.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T03:01:47.730255Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.