7.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance agent · skin conditioning agent · antioxidant · anti-inflammatory · astringent
Vetiveria Zizanioides Root Extract Acetylated
Category
plant extract
Bottom Line: Vetiveria Zizanioides Root Extract Acetylated is generally considered safe for use in cosmetics and food, though individual reactions may vary.
Quick Answer
✔ Generally Safe If:
- used in recommended concentrations
- not applied to broken skin
- used in well-formulated products
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- you are pregnant or nursing
- you are using other active ingredients
✕ Avoid If:
- you have a known allergy to vetiver
- you experience irritation upon use
- you are using it in high concentrations
Chemical Properties
| Property | Value |
|---|
Common Use Cases
4 Categories
Cosmetic
Facial creams, shampoos, body lotions. Generally safe for topical use; patch test recommended.
Food
Flavoring agents, herbal teas. Use in moderation; consult a healthcare provider if unsure.
Pharmaceutical
Herbal supplements, topical treatments. Consult a healthcare professional before use.
Supplement
Dietary supplements, aromatherapy oils. Follow dosage recommendations; monitor for side effects.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to Vetiveria Zizanioides Root Extract is generally well tolerated.
oral
oral
Risk Level: Moderate
Oral ingestion may pose moderate risks due to potential gastrointestinal effects.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk but may cause irritation in sensitive individuals.
ocular
ocular
Risk Level: Very Low
Ocular exposure is generally very low risk, though irritation may occur.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to extracts may lead to adverse effects.
- pregnant — Limited safety data necessitates caution.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal adverse effects.
- elderly — Generally well tolerated; monitor for reactions.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Adults typically tolerate Vetiveria Zizanioides Root Extract well. |
| pregnant | Moderate | Limited data on safety during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to extracts; potential for adverse effects. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| elderly | Low | Elderly individuals generally tolerate this extract well. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Research indicates that Vetiveria Zizanioides Root Extract Acetylated is safe for cosmetic and food use, with minimal reported adverse effects.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | Not available | Insufficient data for acute toxicity | CIR Safety Assessment (2012) |
| Skin Irritation | Non-irritating | Human patch test | Low irritation potential | SCCS Opinion (2015) |
| Sensitization | Not sensitizing | Human clinical study | No sensitization observed | EFSA Opinion (2018) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Research indicates that Vetiveria Zizanioides Root Extract Acetylated is safe for cosmetic and food use, with minimal reported adverse effects.
- Widely used in cosmetics for fragrance and skin benefits.
- Generally recognized as safe in food applications.
- Limited reports of adverse reactions.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Vetiver Oil
Year: 2012
Conclusion: Safe for use in cosmetics at concentrations up to 10%.
View Full Report →
SCCS
Report: Opinion on Vetiver Oil
Year: 2015
Conclusion: Considered safe for cosmetic use with no significant health risks.
View Full Report →
EFSA
Report: Scientific Opinion on Flavoring
Year: 2018
Conclusion: Safe for use as a flavoring agent in food.
View Full Report →
Regulatory Status
Global
Vetiveria Zizanioides Root Extract Acetylated is permitted in major jurisdictions with no significant restrictions. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionPERMITTED
None
UK
UK GovernmentPERMITTED
None
CA
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform a patch test.
Consult a healthcare provider before using any new products during pregnancy.
It is known for its calming aroma and potential skin benefits, but more research is needed.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T08:30:26.706170Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.